Associations of poor water, sanitation, and hygiene and parasite burden with markers of environmental enteric dysfunction in preschool‐age children infected with <i>Schistosoma mansoni</i> in Uganda
Few studies have investigated schistosomiasis-related morbidities in very young children infected with schistosomiasis. Our findings from Uganda show that poor water, sanitation and hygiene conditions and heavier schistosomiasis burden are associated with intestinal inflammation and damage, contributing to EED. Improved treatment coverage for preschool-aged children infected with schistosomiasis may reduce the burden from EED and associated long-term morbidities.
Authors
- Emily L. Webb (ORCID: https://orcid.org/0000-0002-4019-7456)
- David P. Lewander
- Hannah Wu
- Jennifer F. Friedman (ORCID: https://orcid.org/0000-0001-5804-9921)
- Patrice A. Mawa (ORCID: https://orcid.org/0000-0002-4819-8904)
- Susannah Colt (ORCID: https://orcid.org/0000-0002-1935-4197)
- Andrew Edielu
- Racheal Nakyesige (ORCID: https://orcid.org/0000-0002-1061-1599)
- Amaya L. Bustinduy (ORCID: https://orcid.org/0000-0001-6131-4159)
- A. Gloria K. Ayebazibwe
Institutions
- Boston Children's Hospital (US)
- Brown University (US)
- Rhode Island Hospital (US)
- London School of Hygiene & Tropical Medicine (GB)
- Medical Research Council (GB)
- Uganda Virus Research Institute (UG)
Publication Details
- Journal
- Tropical Medicine & International Health
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1111/tmi.14061
- Citations
- 2
- Primary Topic
- Child Nutrition and Water Access
- Type
- article
- Field-Weighted Citation Impact
- 0.62
Funders
- Brown University
- Texas Children's Hospital
- National Institutes of Health
- Medical Research Council
- Center for International Health
- National Institute of Child Health and Human Development