Evaluation of antioxidant and Anti-inflammatoryactivities ofCassia siamea Lam.and Asystasia gangetica(L.) T. Anders

Antioxidant systems play a crucial role in protecting membranes from the deleterious free radicles.Natural, plant derived antioxidants are now preferred to the synthetic ones because of safety concerns.Leaf extracts of Cassia siamea Lam. and Asystasia gangetica (L.) T. Anders were tested for antioxidant and anti-inflammatory components and compared with those of the standard free radicle scavenging compounds like BHT, toluene and Ascorbic acid.Methanolic leaf extracts exhibited strong membrane stabilizing activity.They were also found to be effective in inhibiting heat induced hemolysis, protein denaturation, COX and LOX activities.Cassia siamea exhibited high levels antioxidant components and a more significant radicle scavenging and membrane stabilizing activity when compared to Asystasia gangetica.

Authors

Publication Details

Journal
African Journal of Biomedical Research
Published
2024-11-20
DOI
https://doi.org/10.53555/ajbr.v27i4s.3921
Primary Topic
Phytochemicals and Antioxidant Activities
Type
article
Field-Weighted Citation Impact
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article

Evaluation of antioxidant and Anti-inflammatoryactivities ofCassia siamea Lam.and Asystasia gangetica(L.) T. Anders

Padmaja Musunuri
African Journal of Biomedical Research
Phytochemicals and Antioxidant Activities
article

Evaluation of antioxidant and Anti-inflammatoryactivities ofCassia siamea Lam.and Asystasia gangetica(L.) T. Anders

Padmaja Musunuri
article en

Abstract

Antioxidant systems play a crucial role in protecting membranes from the deleterious free radicles.Natural, plant derived antioxidants are now preferred to the synthetic ones because of safety concerns.Leaf extracts of Cassia siamea Lam. and Asystasia gangetica (L.) T. Anders were tested for antioxidant and anti-inflammatory components and compared with those of the standard free radicle scavenging compounds like BHT, toluene and Ascorbic acid.Methanolic leaf extracts exhibited strong membrane stabilizing activity.They were also found to be effective in inhibiting heat induced hemolysis, protein denaturation, COX and LOX activities.Cassia siamea exhibited high levels antioxidant components and a more significant radicle scavenging and membrane stabilizing activity when compared to Asystasia gangetica.

African Journal of Biomedical Research
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Phytochemicals and Antioxidant Activities
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