Analysis of the Potential Link Between Dermatomyositis and Cancer
The findings demonstrate that MIF, C1QA, and CDKN1A are differentially expressed in DM patients, with MIF showing significant alterations in DM patients with cancer. MIF may serve as a crucial prognostic biomarker and therapeutic target for various cancers, playing a pivotal role in linking DM to cancer through the modulation of CD4+ Th1 cells, NKT cells, and MDSCs.
Authors
- Hongyuan Xie
- Quan‐Bo Zhang (ORCID: https://orcid.org/0000-0001-8559-1927)
- Jianwei Guo (ORCID: https://orcid.org/0009-0009-3753-8561)
- Tianyi Lei
- Yufeng Qing (ORCID: https://orcid.org/0000-0001-6709-7570)
- Xiang Yu (ORCID: https://orcid.org/0000-0002-7387-1603)
- Guilin Jian
- Peng Wang (ORCID: https://orcid.org/0000-0001-7136-9401)
Institutions
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jir.s480744
- Citations
- 2
- Primary Topic
- Macrophage Migration Inhibitory Factor
- Type
- article
- Field-Weighted Citation Impact
- 0.48