Revisiting Antibiotic-Impregnated Cement Spacer for Diabetic Osteomyelitis of the Foot

ACS has shown excellent results in eradicating bone infection with up to 7.23 years of follow-up, acting as a structural stabilizer, preventing soft tissue contractures, and delivering highly concentrated local antibiotic treatment both to soft tissue and bone. Regardless, specific factors should be thoroughly evaluated prior to surgery, as advancing age, gender, and the use of gentamicin-only antibiotics appear to be positively associated with a higher likelihood of reoperation. Conversely, infections caused by cultured <i>Staphylococcus aureus</i> seem to be inversely related to reoperation.