Genetic Variants in the Adhesive G Protein-Coupled Receptor ADGRG6 are Associated with Increased Susceptibility to COPD in the Elderly Han Chinese Population of Southern China
The mutant allele "C" and mutant genotype "CA" of rs11155242 act as protective genetic factors against COPD susceptibility. This study will provide a new research direction for the personalized prevention and treatment of COPD in the elderly Han population in southern China, and lay a potential scientific basis.
Authors
- Linhui Huang (ORCID: https://orcid.org/0000-0002-4529-3455)
- Yipeng Ding (ORCID: https://orcid.org/0009-0009-8646-4028)
- Xiuxiu Ding (ORCID: https://orcid.org/0009-0006-0955-0916)
- Jie Zhao (ORCID: https://orcid.org/0000-0002-7350-4088)
- Tian Xie (ORCID: https://orcid.org/0000-0002-9422-6443)
- Rubing Mo (ORCID: https://orcid.org/0000-0002-9922-2281)
- Yue Zhang (ORCID: https://orcid.org/0000-0002-1161-0141)
- Fei Chen (ORCID: https://orcid.org/0000-0002-1850-7948)
Institutions
- Hainan General Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- International Journal of COPD
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/copd.s478095
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- National Natural Science Foundation of China