Serum protein risk stratification score for diagnostic evaluation of metabolic dysfunction–associated steatohepatitis
The MASH Dx score offers the first reliable noninvasive approach combining novel, biologically plausible ELISA-based fibrosis markers and clinical parameters to detect high-risk MASH in patient cohorts from the United States, Brazil, and Europe.
Authors
- Hasan H. Otu (ORCID: https://orcid.org/0000-0002-9253-8152)
- Simon T. Dillon (ORCID: https://orcid.org/0000-0002-4417-178X)
- Detlef Schuppan (ORCID: https://orcid.org/0000-0002-4972-1293)
- Handan Can (ORCID: https://orcid.org/0000-0003-4991-9803)
- Yuyan Xu (ORCID: https://orcid.org/0000-0003-3335-1248)
- Noel Yan‐Ki Chan
- Nathalie Carvalho Leite (ORCID: https://orcid.org/0000-0001-9066-0405)
- Tina L. Morhardt
- Nezam H. Afdhal (ORCID: https://orcid.org/0000-0002-7342-6593)
- Cláudia Cravo Moreira
- Michelle Lai (ORCID: https://orcid.org/0000-0003-0876-5676)
- Cristiane Alves Villela‐Nogueira (ORCID: https://orcid.org/0000-0003-1355-2368)
- Towia Aron Libermann (ORCID: https://orcid.org/0000-0002-4006-8179)
- Jörn M. Schattenberg (ORCID: https://orcid.org/0000-0002-4224-4703)
- Xuehong Zhang (ORCID: https://orcid.org/0000-0002-8260-8508)
- Lina Jin (ORCID: https://orcid.org/0000-0002-8961-2809)
- Long Ngo (ORCID: https://orcid.org/0000-0002-8903-9352)
- Beibei Xiong
- Xuesong Gu
Institutions
- University of Nebraska–Lincoln (US)
- Universidade Federal do Rio de Janeiro (BR)
- Brigham and Women's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Saarland University (DE)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1097/hc9.0000000000000586
- Citations
- 9
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.48
Funders
- U.S. Department of Defense
- Falk Foundation
- Pfizer
- Sanofi
- Gilead Sciences
- Intercept Pharmaceuticals
- Deutsche Forschungsgemeinschaft
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Novo Nordisk
- National Institutes of Health
- National Cancer Institute