Modeling metabolic-associated steatohepatitis with human pluripotent stem cell-derived liver organoids
This study offers an improved HLO disease model of human MASH, which can be potentially applied to facilitate the understanding of the MASH pathogenesis and the discovery of effective treatments.
Authors
- Yanhao Chen (ORCID: https://orcid.org/0000-0002-5300-8626)
- Yuchen Wang (ORCID: https://orcid.org/0000-0002-4875-2995)
- Yi Yang (ORCID: https://orcid.org/0000-0001-7896-1184)
- Chunping Jiang (ORCID: https://orcid.org/0000-0001-7746-387X)
- Dacheng Jiang (ORCID: https://orcid.org/0000-0002-7006-9754)
- Qiurong Ding (ORCID: https://orcid.org/0000-0001-9906-6787)
- Xiaosong Gu (ORCID: https://orcid.org/0000-0002-2562-6275)
- Ruikun He
- Wei Sun (ORCID: https://orcid.org/0009-0004-8139-591X)
- Xiaoshan Wu (ORCID: https://orcid.org/0000-0001-7917-801X)
- Xin Li (ORCID: https://orcid.org/0000-0003-3675-8465)
- C Liu
Institutions
- East China University of Science and Technology (CN)
- Shanghai Institute of Nutrition and Health (CN)
- Shanghai Institutes for Biological Sciences (CN)
- Nanjing Drum Tower Hospital (CN)
- University of Chinese Academy of Sciences (CN)
- Xiaomi (China) (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1097/hc9.0000000000000585
- Citations
- 4
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.55