Transcranial Magnetic Stimulation Attenuates Dyskinesias and FosB and c-Fos Expression in a Parkinson’s Disease Model
The current study shows that TMS depressed FosB and c-Fos expression in D1R+ cells of the dorsal striatum and motor cortex, in accordance with previous evidence of its capacity to modulate the dopaminergic system, thus suggesting a mechanism by which TMS may mitigate dyskinesias. Additionally, our observations highlight the potential therapeutic effect of TMS on dyskinesias in a PD model.
Authors
- Marcela Palomero‐Rivero
- Gabriel Roldán-Roldán (ORCID: https://orcid.org/0000-0003-1356-6428)
- Isaac Túnez‐Fiñana
- Diana Millán‐Aldaco (ORCID: https://orcid.org/0000-0001-5801-1595)
- Fernanda Ramirez‐López (ORCID: https://orcid.org/0000-0001-7786-6361)
- José Rubén García-Montes (ORCID: https://orcid.org/0000-0002-9263-0995)
- René Drucker‐Colín
Institutions
- Instituto Cajal (ES)
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- University of Córdoba (ES)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Brain Sciences
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3390/brainsci14121214
- Citations
- 2
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.49
Funders
- Consejo Nacional de Ciencia y Tecnología
- Universidad Nacional Autónoma de México