Visible-light-induced cascade radical cyclization to access sulfamoylated benzo[4,5]imidazo[2,1-<i>a</i>]isoquinolin-6(5<i>H</i>)-ones

We report, for the first time, a visible-light-induced cascade radical sulfamoylation and cyclization of 2-arylbenzoimidazoles using sulfamoyl chlorides as sulfamoylation reagents to access sulfamoylated benzo[4,5]imidazo[2,1-<i>a</i>]isoquinolin-6(5<i>H</i>)-ones. The readily available nature of sulfamoyl chlorides and the metal-free conditions make this method a promising strategy for the synthesis of these compounds.

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Publication Details

Journal
Organic & Biomolecular Chemistry
Published
2024-12-03
DOI
https://doi.org/10.1039/d4ob01809e
Citations
3
Primary Topic
Sulfur-Based Synthesis Techniques
Type
article
Field-Weighted Citation Impact
0.75

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article

Visible-light-induced cascade radical cyclization to access sulfamoylated benzo[4,5]imidazo[2,1-a]isoquinolin-6(5H)-ones

Kui Lu, Xia Zhao, Rong Huang, Wenbo Wang
3 citations
Organic & Biomolecular Chemistry
Sulfur-Based Synthesis Techniques
0.75
article

Visible-light-induced cascade radical cyclization to access sulfamoylated benzo[4,5]imidazo[2,1-a]isoquinolin-6(5H)-ones

Kui Lu, Xia Zhao, Rong Huang, Wenbo Wang
article en
3 citations

Abstract

We report, for the first time, a visible-light-induced cascade radical sulfamoylation and cyclization of 2-arylbenzoimidazoles using sulfamoyl chlorides as sulfamoylation reagents to access sulfamoylated benzo[4,5]imidazo[2,1-<i>a</i>]isoquinolin-6(5<i>H</i>)-ones. The readily available nature of sulfamoyl chlorides and the metal-free conditions make this method a promising strategy for the synthesis of these compounds.

Organic & Biomolecular ChemistryVol. 23(4)
Tianjin University of Science and Technology (CN), Tianjin Normal University (CN), China International Science and Technology Cooperation (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 31%
Sulfur-Based Synthesis Techniques
0.75
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