A preclinical and phase I clinical study of ex vivo-expanded amyloid beta-specific human regulatory T cells in Alzheimer’s disease
Title: A Study of Possibility of Using Regulatory T Cells (VT301) for Treatment of Alzheimer's Disease, ClinicalTrials.gov NCT05016427, Study approval date: Ministry of Food and Drug Safety of the Republic of Korea (MFDS) - August 31st, 2020, Institutional Review Board (IRB) of Seoul National University Hospital, Republic of Korea - September 29th, 2020, The date of first patient enrollment: December 7th, 2020. https://clinicaltrials.gov/study/NCT05016427.
Authors
- Young‐Tae Chang (ORCID: https://orcid.org/0000-0002-1927-3688)
- Jee Eun Park (ORCID: https://orcid.org/0000-0001-6097-3275)
- Min Soo Byun (ORCID: https://orcid.org/0000-0003-3159-4510)
- Jae Yoon Kim (ORCID: https://orcid.org/0000-0003-3012-8200)
- Hyunsu Bae (ORCID: https://orcid.org/0000-0002-0299-3582)
- Na-Yeon Ha (ORCID: https://orcid.org/0000-0001-6611-0147)
- Juwon Yang (ORCID: https://orcid.org/0009-0008-8460-8027)
- Dahyun Yi (ORCID: https://orcid.org/0000-0002-0860-0946)
- Woo Sang Jung (ORCID: https://orcid.org/0000-0002-0727-3744)
- Seon‐Young Park (ORCID: https://orcid.org/0000-0002-0962-5977)
- Dong Young Lee (ORCID: https://orcid.org/0000-0001-8976-8320)
- Jinsung Kim (ORCID: https://orcid.org/0000-0001-5135-3699)
- Hyejin Yang (ORCID: https://orcid.org/0000-0002-5238-7820)
Institutions
- Pohang University of Science and Technology (KR)
- Seoul National University (KR)
- Seoul National University Hospital (KR)
- Kyung Hee University (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.biopha.2024.117721
- Citations
- 5
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.24