A randomized controlled trial on single-session mindfulness self-compassion interventions for Fibromyalgia Syndrome: evaluating interoceptive awareness, anxiety, and pain

Abstract Objectives: This randomized controlled trial evaluates a single-session Mindfulness Self-Compassion (MSC) intervention for enhancing interoceptive awareness (AI) and alleviating anxiety and reducing pain in Fibromyalgia Syndrome (FMS) patients. The study also examines the intervention’s feasibility and the mediating role of IA in improving clinical outcomes, incorporating nature visuals to address treatment accessibility and adherence. Methods/analysis: Sixty-four FMS patients were randomized into three groups: MSC with audio-only, MSC with audio and nature visuals, or a waitlist control. Validated scales measured interoceptive awareness, anxiety, and pain pre- and post-intervention. ANOVA examined primary outcomes, and mediation analysis explored interoceptive awareness as a mediator. A 7-minute intervention duration was chosen for its balance of effectiveness and feasibility, with nature visuals selected for their calming effects. Findings: Both MSC groups showed significant improvements in IA, anxiety, and pain compared to the control group, with the audio-visual group showing the strongest effects. Enhanced interoceptive awareness significantly mediated anxiety reduction but not pain relief. Nature visuals further reduced anxiety and pain compared to audio-only. Novelty/improvement: This study validates the efficacy of a single-session MSC intervention for FMS, highlighting IA as a crucial mediator of anxiety improvement. Incorporating sensory-rich visual elements enhances therapeutic effects, offering a promising approach for MSC interventions in clinical settings. Future research should explore long-term benefits and optimal dosage of this innovative intervention, addressing the need for accessible, cost-effective FMS treatments.