Remimazolam for Sedation During Magnetic Resonance Imaging in a Toddler With an Acute COVID-19 Infection

The coronavirus disease 2019 (COVID-19) pandemic has led to a global surge in hospitalizations due to pneumonia and respiratory distress. As with other infectious medical conditions, the perioperative care of a patient with an active or recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection must address concerns regarding both the healthcare providers and the patient. SARS-CoV-2-positive patients face a higher risk of pulmonary complications and significantly higher rates of mortality, especially in those with preoperative respiratory symptoms. We present the use of the novel benzodiazepine, remimazolam, to provide sedation in a 9-month-old child with a fever of 106 ¡ãF who required sedation and anesthetic care during magnetic resonance imaging following a seizure. The basic pharmacology of remimazolam is discussed, previous reports of its use for procedure sedation are reviewed, and dosing regimens are presented. Int J Clin Pediatr. 2024;13(3):101-104 doi: https://doi.org/10.14740/ijcp541

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Journal
International Journal of Clinical Pediatrics
Published
2024-12-01
DOI
https://doi.org/10.14740/ijcp541
Primary Topic
Anesthesia and Sedative Agents
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article
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article

Remimazolam for Sedation During Magnetic Resonance Imaging in a Toddler With an Acute COVID-19 Infection

Ajay D’Mello, Elisa Villalobos, Joseph D. Tobias
International Journal of Clinical Pediatrics
Anesthesia and Sedative Agents
article

Remimazolam for Sedation During Magnetic Resonance Imaging in a Toddler With an Acute COVID-19 Infection

Ajay D’Mello, Elisa Villalobos, Joseph D. Tobias
article en

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has led to a global surge in hospitalizations due to pneumonia and respiratory distress. As with other infectious medical conditions, the perioperative care of a patient with an active or recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection must address concerns regarding both the healthcare providers and the patient. SARS-CoV-2-positive patients face a higher risk of pulmonary complications and significantly higher rates of mortality, especially in those with preoperative respiratory symptoms. We present the use of the novel benzodiazepine, remimazolam, to provide sedation in a 9-month-old child with a fever of 106 ¡ãF who required sedation and anesthetic care during magnetic resonance imaging following a seizure. The basic pharmacology of remimazolam is discussed, previous reports of its use for procedure sedation are reviewed, and dosing regimens are presented. Int J Clin Pediatr. 2024;13(3):101-104 doi: https://doi.org/10.14740/ijcp541

International Journal of Clinical PediatricsVol. 13(3)
Nationwide Children's Hospital (US)
Good health and well-being
Openalex Percentile: Top 60%
Anesthesia and Sedative Agents
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