Ginsenoside Rb1 affects mitochondrial Ca2+ transport and inhibits fat deposition and fibrosis by regulating the wnt signaling pathway to treat rotator cuff tears via docking with SFRP1
Ginsenoside Rb1 inhibited the activation of the Wnt signaling pathway by promoting SFRP1 expression, thereby inhibiting mitochondrial function and Ca<sup>2+</sup> absorption to treat fat infiltration and muscle fibrosis caused by RCTs.
Authors
- Song Wu
- Hai Hu (ORCID: https://orcid.org/0000-0002-6985-8959)
- Yian Yang
- Yuesong Yin
Institutions
- Central South University (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-12-02
- DOI
- https://doi.org/10.1186/s10020-024-01009-0
- Citations
- 5
- Primary Topic
- Shoulder Injury and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- National Natural Science Foundation of China