Chlorogenic acid alleviates IPEC-J2 pyroptosis induced by deoxynivalenol by inhibiting activation of the NF-κB/NLRP3/caspase-1 pathway
Pretreatment with 80 μmol/L CGA for 4 h effectively alleviated pyroptosis in IPEC-J2 cells induced by 2,500 ng/mL of DON through inhibiting activation of the NF-κB/ NLRP3/capase-1 pathway.
Authors
- Huijun Guo (ORCID: https://orcid.org/0000-0001-9407-7479)
- Yanmei Xue (ORCID: https://orcid.org/0000-0002-3732-3423)
- Xinru Zhang (ORCID: https://orcid.org/0000-0003-0643-390X)
- Fuchang Li (ORCID: https://orcid.org/0000-0002-5670-8038)
- Chunyang Wang (ORCID: https://orcid.org/0000-0002-6707-2274)
- Rui Li (ORCID: https://orcid.org/0000-0003-2545-8184)
Institutions
- Shandong Agricultural University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2024-12-02
- DOI
- https://doi.org/10.1186/s40104-024-01119-z
- Citations
- 14
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.27
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province