Diploid fetus with partially triploid placenta: case presentation and management strategy

Multiple placental cysts are a common finding in obstetric ultrasound imaging. Although they have benign differential diagnoses, such as hydropic degeneration of the placenta or placental mesenchymal dysplasia, it's important to consider significant pathologies, such as benign gestational trophoblastic disease or hydatidiform mole. A challenging issue in obstetrics is pregnancies with a placenta that has a bipartite texture. This means that one side of the placenta is normal, but the other side is full of cystic formations, and only one fetus is visualized. The main critical concern is the presence of a molar pregnancy because of its catastrophic consequences. Here, we report a rare case in which the gravid uterus had a normal diploid fetus but had a bipartite placenta, which was triploid in the hydropic part, revealing a unique genetic pattern.

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Publication Details

Journal
Maternal Health Neonatology and Perinatology
Published
2024-12-01
DOI
https://doi.org/10.1186/s40748-024-00195-3
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
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article

Diploid fetus with partially triploid placenta: case presentation and management strategy

Fariba Yarandi, Fatemeh Golshahi, Ali Rashidi‐Nezhad, Behrokh Sahebdel et al.
Maternal Health Neonatology and Perinatology
Gestational Trophoblastic Disease Studies
article

Diploid fetus with partially triploid placenta: case presentation and management strategy

Fariba Yarandi, Fatemeh Golshahi, Ali Rashidi‐Nezhad, Behrokh Sahebdel, Elham Shirali, Nafiseh Saedi, Ehsan Sobhanian, Zahra Moghimi, Mahmoud Shirazi
article en

Abstract

Multiple placental cysts are a common finding in obstetric ultrasound imaging. Although they have benign differential diagnoses, such as hydropic degeneration of the placenta or placental mesenchymal dysplasia, it's important to consider significant pathologies, such as benign gestational trophoblastic disease or hydatidiform mole. A challenging issue in obstetrics is pregnancies with a placenta that has a bipartite texture. This means that one side of the placenta is normal, but the other side is full of cystic formations, and only one fetus is visualized. The main critical concern is the presence of a molar pregnancy because of its catastrophic consequences. Here, we report a rare case in which the gravid uterus had a normal diploid fetus but had a bipartite placenta, which was triploid in the hydropic part, revealing a unique genetic pattern.

Maternal Health Neonatology and PerinatologyVol. 10(1)
Children's Medical Center (IR), Tehran University of Medical Sciences (IR)
Zero hunger
Openalex Percentile: Top 67%
Gestational Trophoblastic Disease Studies
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