Comprehensive pathogen identification and antimicrobial resistance prediction from positive blood cultures using nanopore sequencing technology
Nanopore sequencing with adaptive sampling can directly analyze positive blood cultures, facilitating pathogen detection, AMR prediction, and outbreak investigation. Integrating nanopore sequencing into clinical practices signifies a revolutionary advancement in managing bloodstream infections, offering an effective antimicrobial stewardship strategy, and improving patient outcomes.
Authors
- Yu-Chieh Liao (ORCID: https://orcid.org/0000-0002-4360-7932)
- Feng-Jui Chen (ORCID: https://orcid.org/0000-0003-2270-2591)
- Ci‐Hong Liou (ORCID: https://orcid.org/0000-0001-6157-5340)
- Hung‐Wei Cheng (ORCID: https://orcid.org/0000-0003-1740-0337)
- Po‐Yu Liu (ORCID: https://orcid.org/0000-0001-8006-4917)
- Han‐Chieh Wu (ORCID: https://orcid.org/0000-0003-2638-7883)
- Yinglan Li
Institutions
- National Yang Ming Chiao Tung University (TW)
- National Chung Hsing University (TW)
- National Health Research Institutes (TW)
- Taichung Veterans General Hospital (TW)
Publication Details
- Journal
- Genome Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1186/s13073-024-01416-2
- Citations
- 18
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 6.86
Funders
- National Health Research Institutes
- Taichung Veterans General Hospital
- National Science and Technology Council