Associations of PFAS concentrations during pregnancy and midlife with bone health in midlife: Cross-sectional and prospective findings from Project Viva
Plasma PFAS measured during pregnancy versus in midlife had different associations with midlife aBMD. We found an adverse association of PFAS measured in midlife with midlife aBMD, particularly among postmenopausal women. Future studies with longer follow-up are needed to elucidate the effect of PFAS on bone health during the peri- and postmenopausal years.
Authors
- Diane R. Gold (ORCID: https://orcid.org/0000-0001-8789-418X)
- Russ Hauser (ORCID: https://orcid.org/0000-0002-1899-3982)
- Abby F. Fleisch (ORCID: https://orcid.org/0000-0002-2789-6412)
- Lisa B. Rokoff
- Sheryl L. Rifas‐Shiman (ORCID: https://orcid.org/0000-0003-0033-920X)
- Thomas F. Webster (ORCID: https://orcid.org/0000-0003-4896-9323)
- Tamarra James‐Todd (ORCID: https://orcid.org/0000-0003-3589-5169)
- Andrés Cárdenas (ORCID: https://orcid.org/0000-0003-2284-3298)
- Emily Oken (ORCID: https://orcid.org/0000-0003-2513-3339)
- Antonia M. Calafat (ORCID: https://orcid.org/0000-0002-9796-7482)
- Ami R. Zota
- Mingyu Zhang (ORCID: https://orcid.org/0000-0003-3628-0983)
- Pi‐I D. Lin (ORCID: https://orcid.org/0000-0003-3564-4255)
- Julianne Cook Botelho (ORCID: https://orcid.org/0000-0002-6740-7169)
Institutions
- Boston University (US)
- Brigham and Women's Hospital (US)
- Centers for Disease Control and Prevention (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- National Center for Environmental Health (US)
- MaineHealth (US)
- Harvard Pilgrim Health Care (US)
- Columbia University (US)
- Stanford University (US)
Publication Details
- Journal
- Environment International
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.envint.2024.109177
- Citations
- 3
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 0.75
Funders
- American Heart Association
- National Institutes of Health
- National Institute of Environmental Health Sciences