Establishing Indicative Neurofilament Gradients Based on Severity of Spinal Cord Injury
A negative correlation was observed between biomarkers and functional outcome scores with statistical significance for the 100 kdyn injury. As such, this study demonstrates the potential usefulness of these biomarkers in SCI, especially with regard to impact severity. Futures studies may be conducted at various impact forces to establish a biomarker gradient based on severity of injury.
Authors
- Yue‐Fang Chang (ORCID: https://orcid.org/0000-0003-0080-4597)
- Tavis Taylor
- Parthasarathy D. Thirumala (ORCID: https://orcid.org/0000-0003-2069-2932)
- G. F. Stout
- Nitin Agarwal (ORCID: https://orcid.org/0000-0002-4684-8774)
- David Kojo Hamilton (ORCID: https://orcid.org/0009-0009-7713-7252)
- A. Krishnamoorthy
- William Rabon
- Megan Rode
- Pallavi Muluk
- Hannah Easow
Institutions
- University of Pittsburgh (US)
- VA Pittsburgh Healthcare System (US)
- University of Pittsburgh Medical Center (US)
- Neurological Surgery (US)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1016/j.wneu.2024.11.098
- Citations
- 2
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- DePuy Synthes Spine