BREAST CANCER SCREENING IN WOMEN AGED 45-65 IN SAMARKAND REGION, UZBEKISTAN: A CROSS-SECTIONAL ANALYSIS OF DATA FROM 2023

Objective: Breast cancer is a leading cause of cancer-related mortality among women globally, and early detection through screening significantly reduces morbidity and mortality. This study evaluates the outcomes of breast cancer screening programs in the Samarkand region of Uzbekistan in 2023, focusing on participation rates, detection rates, and stage distribution across 17 districts and cities. Methods: Data were collected on women aged 45–65, including annual screening targets, the number of screenings performed, diagnosed cases, and cancer stage distribution (early stages 1–2 vs. late stages 3–4). Statistical analysis was conducted to determine completion and detection rates, as well as regional disparities in screening outcomes. Results: The screening program achieved promising outcomes in participation and early-stage cancer detection, with substantial variability among districts. A higher proportion of cases were detected at stages 1–2, indicating effective early diagnosis in some areas. However, significant regional disparities in screening completion and detection highlight inequitable access to services. Novelty: This study provides a comprehensive regional analysis of breast cancer screening outcomes in Uzbekistan, emphasizing the importance of addressing disparities to improve equitable access to early diagnosis and treatment. These findings underscore the need for targeted public health interventions to enhance program effectiveness and reduce the burden of late-stage breast cancer