Alzheimer's disease drug development in an evolving therapeutic landscape

The Alzheimer's Association Research Roundtable (AARR) convened leaders from industry and academia, as well as patients, clinicians, and government and regulatory agency scientists to discuss the topic, "Alzheimer's Disease Drug Development in an Evolving Therapeutic Landscape."While recently approved amyloid-targeting therapies show great promise in providing clinically meaningful outcomes for patients and families, additional treatments, and a better understanding of dosing and administration of these approved treatments, are needed to further slow and eventually prevent clinical decline in AD.Approved therapies will impact many aspects of clinical trial design including the use of placebo-controls, participant re-enrollment, safety monitoring, as well as biomarker selection.This exciting new era in AD research represents a hopeful future for clinicians, patients, and their care partners.

Authors

Institutions

Publication Details

Journal
Alzheimer s & Dementia Translational Research & Clinical Interventions
Published
2024-10-01
DOI
https://doi.org/10.1002/trc2.70015
Citations
2
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
0.72
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Alzheimer's disease drug development in an evolving therapeutic landscape

Christopher J. Weber, Adam Fleisher, Paul Maruff, Stacie Weninger et al.
2 citations
Alzheimer s & Dementia Translational Research & Clinical Interventions
Computational Drug Discovery Methods
0.72
article

Alzheimer's disease drug development in an evolving therapeutic landscape

Christopher J. Weber, Adam Fleisher, Paul Maruff, Stacie Weninger, Teresa León, Sheila Seleri, David S. Miller, Marı́a C. Carrillo, Michael C. Irizarry
article en
2 citations

Abstract

The Alzheimer's Association Research Roundtable (AARR) convened leaders from industry and academia, as well as patients, clinicians, and government and regulatory agency scientists to discuss the topic, "Alzheimer's Disease Drug Development in an Evolving Therapeutic Landscape."While recently approved amyloid-targeting therapies show great promise in providing clinically meaningful outcomes for patients and families, additional treatments, and a better understanding of dosing and administration of these approved treatments, are needed to further slow and eventually prevent clinical decline in AD.Approved therapies will impact many aspects of clinical trial design including the use of placebo-controls, participant re-enrollment, safety monitoring, as well as biomarker selection.This exciting new era in AD research represents a hopeful future for clinicians, patients, and their care partners.

Alzheimer s & Dementia Translational Research & Clinical InterventionsVol. 10(4)
Alzheimer's Association (US), Eli Lilly (United States) (US), Novo Nordisk (Denmark) (DK), Connecticut Sea Grant (US), Eisai (United States) (US)
Openalex Percentile: Top 24%
Computational Drug Discovery Methods
0.72
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Alzheimer's disease drug development in an evolving therapeutic landscape — Christopher J. Weber, Adam Fleisher, et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions (2024) | TGRS Research Map | TGRS