Repeated Cerebral Thrombophlebitis and Pregnancy: A Case Report with Literature Review

Cerebral thrombophlebitis (CVT) that occurs during pregnancy is rarer than postpartum thrombophlebitis.The main risk factors are pregnancy and thrombophilia.Symptoms vary and may be misleading.It is necessary to discuss its diagnosis to start an early anticoagulation.We report the case of a 33-year-old pregnant woman, who had a history of postpartum cerebral thrombophlebitis in her second pregnancy, and presented at 15 weeks of amenorrhea in a disorder of consciousness associated with partial seizures becoming generalized, due to vein thrombosis of the right lateral sinus diagnosed with MRI, with a normal thrombophilia balance, through this observation, we analyse the clinical, paraclinical characteristics and the evolution of CVT during pregnancy.The current gold standard is based on a combination of MRI and magnetic resonance venography.Treatment involves curative anticoagulation, continued for at least 6 months postpartum.The prognosis is generally favourable, ensured by early diagnosis and anticoagulant treatment.CVT, including that related to pregnancy or postpartum, does not contraindicate future pregnancies.For pregnant patients with a history of CVT in previous pregnancies, prophylaxis with low molecular weight heparin (LMWH) is recommended and should be continued for at least six weeks after delivery.

Publication Details

Journal
Annals of Case Reports
Published
2024-11-19
DOI
https://doi.org/10.29011/2574-7754.102074
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
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article

Repeated Cerebral Thrombophlebitis and Pregnancy: A Case Report with Literature Review

Annals of Case Reports
Blood Coagulation and Thrombosis Mechanisms
article

Repeated Cerebral Thrombophlebitis and Pregnancy: A Case Report with Literature Review

article en

Abstract

Cerebral thrombophlebitis (CVT) that occurs during pregnancy is rarer than postpartum thrombophlebitis.The main risk factors are pregnancy and thrombophilia.Symptoms vary and may be misleading.It is necessary to discuss its diagnosis to start an early anticoagulation.We report the case of a 33-year-old pregnant woman, who had a history of postpartum cerebral thrombophlebitis in her second pregnancy, and presented at 15 weeks of amenorrhea in a disorder of consciousness associated with partial seizures becoming generalized, due to vein thrombosis of the right lateral sinus diagnosed with MRI, with a normal thrombophilia balance, through this observation, we analyse the clinical, paraclinical characteristics and the evolution of CVT during pregnancy.The current gold standard is based on a combination of MRI and magnetic resonance venography.Treatment involves curative anticoagulation, continued for at least 6 months postpartum.The prognosis is generally favourable, ensured by early diagnosis and anticoagulant treatment.CVT, including that related to pregnancy or postpartum, does not contraindicate future pregnancies.For pregnant patients with a history of CVT in previous pregnancies, prophylaxis with low molecular weight heparin (LMWH) is recommended and should be continued for at least six weeks after delivery.

Annals of Case ReportsVol. 9(6)
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Blood Coagulation and Thrombosis Mechanisms
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