Protein C Deficiency Associated with Postpartum Cerebral Thrombophlebitis: A Case Report with Literature Review

This article presents a comprehensive overview of a case report and literature review on postpartum cerebral thrombophlebitis revealing protein C deficiency.The case involves a 32-year-old woman who developed cerebral venous thrombosis (CVT) in the postpartum period, associated with severe headaches, visual disturbances, and lower limb weakness.Diagnostic investigations confirmed protein C deficiency, a rare genetic disorder that predisposes individuals to abnormal blood clot formation.The patient was treated with anticoagulation therapy with good outcome, highlighting the critical importance of early recognition and management of protein C deficiency to mitigate life-threatening thrombotic complications.The article emphasizes the significance of understanding the interplay between protein C deficiency and cerebrovascular disorders, particularly during pregnancy and the postpartum period.The findings underscore the need for heightened clinical awareness, timely intervention, and further research to enhance our understanding of protein C deficiency and its management, especially in the context of pregnancy-related complications.

Publication Details

Journal
Annals of Case Reports
Published
2024-11-19
DOI
https://doi.org/10.29011/2574-7754.102073
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
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article

Protein C Deficiency Associated with Postpartum Cerebral Thrombophlebitis: A Case Report with Literature Review

Annals of Case Reports
Blood Coagulation and Thrombosis Mechanisms
article

Protein C Deficiency Associated with Postpartum Cerebral Thrombophlebitis: A Case Report with Literature Review

article en

Abstract

This article presents a comprehensive overview of a case report and literature review on postpartum cerebral thrombophlebitis revealing protein C deficiency.The case involves a 32-year-old woman who developed cerebral venous thrombosis (CVT) in the postpartum period, associated with severe headaches, visual disturbances, and lower limb weakness.Diagnostic investigations confirmed protein C deficiency, a rare genetic disorder that predisposes individuals to abnormal blood clot formation.The patient was treated with anticoagulation therapy with good outcome, highlighting the critical importance of early recognition and management of protein C deficiency to mitigate life-threatening thrombotic complications.The article emphasizes the significance of understanding the interplay between protein C deficiency and cerebrovascular disorders, particularly during pregnancy and the postpartum period.The findings underscore the need for heightened clinical awareness, timely intervention, and further research to enhance our understanding of protein C deficiency and its management, especially in the context of pregnancy-related complications.

Annals of Case ReportsVol. 9(6)
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Blood Coagulation and Thrombosis Mechanisms
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