Impacts of informant replacement in two industry‐sponsored Alzheimer's disease clinical trials
Informant replacement occurred in 2.6% of participants in these industry trials.Informant replacement was associated with increased variance in acute Alzheimer's Disease Cooperative Study Activities of Daily Living reporting.Informant replacement had a limited impact on overall change-from-baseline outcomes.
Authors
- M. Nishida (ORCID: https://orcid.org/0009-0007-8676-9361)
- Joshua D. Grill (ORCID: https://orcid.org/0000-0002-4215-7589)
- Michelle M. Nuño (ORCID: https://orcid.org/0000-0003-2031-929X)
- Daniel L. Gillen (ORCID: https://orcid.org/0000-0003-1983-9730)
Institutions
- University of Southern California (US)
- University of California, Irvine (US)
Publication Details
- Journal
- Alzheimer s & Dementia Translational Research & Clinical Interventions
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/trc2.70009
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39