Molecular Ultrasound Imaging With Clinically Translatable cRGD-Coated Microbubbles to Assess αvβ3-Integrin Expression in Inflammatory Bowel Disease
Integrin-α v β 3 on vessels is a suitable marker for IBD. USMI using cRGD-MB accurately detects this marker and correlates well with histology. These encouraging results support clinical translation of this imaging method as a noninvasive and cost-effective monitoring tool.
Authors
- Yang Shi (ORCID: https://orcid.org/0000-0003-4530-2056)
- Jinwei Qi
- Fabian M. Kiessling (ORCID: https://orcid.org/0000-0002-7341-0399)
- Saskia von Stillfried (ORCID: https://orcid.org/0000-0002-5260-8494)
- Anne Rix (ORCID: https://orcid.org/0000-0003-2624-046X)
- Junlin Chen (ORCID: https://orcid.org/0000-0002-0328-6898)
- Patrick Kozcera
Institutions
- RWTH Aachen University (DE)
Publication Details
- Journal
- Investigative Radiology
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1097/rli.0000000000001143
- Citations
- 3
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.65