Role of the liver in the sustained normalisation of A1c over 2 years following short‐term insulin therapy in early type 2 diabetes
While lower baseline A1c and greater reduction in central adiposity predicted A1c <6.0% at 2 years as anticipated, the emergence of greater reduction in ALT as a concomitant determinant highlights the role of the liver in the achievement of sustained glycaemic normalisation.
Authors
- Sonja M. Reichert (ORCID: https://orcid.org/0000-0003-3914-7010)
- Natalia McInnes (ORCID: https://orcid.org/0000-0003-1495-3825)
- Jiajie Pu (ORCID: https://orcid.org/0009-0008-1229-0734)
- Hertzel C. Gerstein (ORCID: https://orcid.org/0000-0001-8072-2836)
- Caroline K. Kramer (ORCID: https://orcid.org/0000-0003-1064-0100)
- Andrew Wu (ORCID: https://orcid.org/0000-0002-0929-1145)
- Ravi Retnakaran (ORCID: https://orcid.org/0000-0003-1989-027X)
- Alexandra Emery
- Bernard Zinman (ORCID: https://orcid.org/0000-0002-0041-1876)
- Stewart B. Harris (ORCID: https://orcid.org/0000-0002-8282-5449)
Institutions
- Western University (CA)
- Mount Sinai Hospital (CA)
- University of Toronto (CA)
- Lunenfeld-Tanenbaum Research Institute (CA)
- McMaster University (CA)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1111/dom.16099
- Citations
- 1
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Sanofi
- McMaster University
- Canadian Institutes of Health Research