Case report: A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature
Solitary fibrous tumors (SFTs) are classified as fibroblastic/myofibroblastic tumors that originate from CD34-positive dendritic cells and usually occur in the pleura. In this paper, we describe a case of SFT within the joint cavity of the left knee. A 60-year-old man was admitted to hospital due to swelling in the left knee for the past 8 months without relevant trauma history. X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography-computed tomography (PET-CT) presented a large, ill-circumscribed, hypervascular, and highly enhanced mass with eccentric calcification and peripheral, intra-lesional vessels. Subsequently, the patient underwent surgical resection. Postoperative pathology confirmed the neoplastic cells to be positive for CD34, Bcl-2, and SATA6, therefore was finally diagnosed as malignant SFT. The patient developed bone metastases within 1 year after surgery. SFT in the joint cavity is rare, and it is difficult to make a preoperative diagnosis.
Authors
- Yao Pan (ORCID: https://orcid.org/0000-0002-8092-4865)
- Xiaojie Wang (ORCID: https://orcid.org/0000-0003-4817-5830)
- Ri-Sheng Yu (ORCID: https://orcid.org/0000-0002-2428-0268)
- Jia-Ping Zhou
Institutions
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3389/fonc.2024.1463362
- Citations
- 1
- Primary Topic
- Soft tissue tumor case studies
- Type
- article
- Field-Weighted Citation Impact
- 0.47