Case report: A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature

Solitary fibrous tumors (SFTs) are classified as fibroblastic/myofibroblastic tumors that originate from CD34-positive dendritic cells and usually occur in the pleura. In this paper, we describe a case of SFT within the joint cavity of the left knee. A 60-year-old man was admitted to hospital due to swelling in the left knee for the past 8 months without relevant trauma history. X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography-computed tomography (PET-CT) presented a large, ill-circumscribed, hypervascular, and highly enhanced mass with eccentric calcification and peripheral, intra-lesional vessels. Subsequently, the patient underwent surgical resection. Postoperative pathology confirmed the neoplastic cells to be positive for CD34, Bcl-2, and SATA6, therefore was finally diagnosed as malignant SFT. The patient developed bone metastases within 1 year after surgery. SFT in the joint cavity is rare, and it is difficult to make a preoperative diagnosis.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-11-29
DOI
https://doi.org/10.3389/fonc.2024.1463362
Citations
1
Primary Topic
Soft tissue tumor case studies
Type
article
Field-Weighted Citation Impact
0.47
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Case report: A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature

Yao Pan, Xiaojie Wang, Ri-Sheng Yu, Jia-Ping Zhou
1 citations
Frontiers in Oncology
Soft tissue tumor case studies
0.47
article

Case report: A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature

Yao Pan, Xiaojie Wang, Ri-Sheng Yu, Jia-Ping Zhou
article en
1 citations

Abstract

Solitary fibrous tumors (SFTs) are classified as fibroblastic/myofibroblastic tumors that originate from CD34-positive dendritic cells and usually occur in the pleura. In this paper, we describe a case of SFT within the joint cavity of the left knee. A 60-year-old man was admitted to hospital due to swelling in the left knee for the past 8 months without relevant trauma history. X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography-computed tomography (PET-CT) presented a large, ill-circumscribed, hypervascular, and highly enhanced mass with eccentric calcification and peripheral, intra-lesional vessels. Subsequently, the patient underwent surgical resection. Postoperative pathology confirmed the neoplastic cells to be positive for CD34, Bcl-2, and SATA6, therefore was finally diagnosed as malignant SFT. The patient developed bone metastases within 1 year after surgery. SFT in the joint cavity is rare, and it is difficult to make a preoperative diagnosis.

Frontiers in OncologyVol. 14
Second Affiliated Hospital of Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 29%
Soft tissue tumor case studies
0.47
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