Prognostic value of B7-H3 expression in metastatic renal cell carcinoma and its impact on immunotherapy response
High B7-H3 expression is associated with poorer survival outcomes and reduced response to nivolumab in metastatic RCC patients. B7-H3 may serve as a predictive biomarker for immunotherapy response. Future studies should explore targeting B7-H3 in combination with existing therapies to enhance treatment efficacy.
Authors
- Hüseyin Salih Semiz (ORCID: https://orcid.org/0000-0002-7083-8517)
- Faruk Recep Özalp (ORCID: https://orcid.org/0000-0002-2863-3243)
- Kutsal Yörükoğlu (ORCID: https://orcid.org/0000-0002-4099-0905)
- Eda Yildirim (ORCID: https://orcid.org/0000-0002-4796-3854)
- Mehmet Uzun (ORCID: https://orcid.org/0000-0003-2999-489X)
Institutions
- Dokuz Eylül University (TR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1186/s12885-024-13238-x
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.13