ID1 and ID3 functions in the modulation of the tumour immune microenvironment in adult patients with B-cell acute lymphoblastic leukaemia
These findings highlight significant differences in ID1 and ID3 expression levels and their impact on TIME populations, particularly neutrophil-related pathways. The results suggest a potential role for ID1 and ID3 in immune evasion in adult B-ALL, mediated through neutrophil activation and immune regulation.
Authors
- Jovanny Zabaleta (ORCID: https://orcid.org/0000-0002-5961-6761)
- Nataly Cruz‐Rodriguez (ORCID: https://orcid.org/0000-0002-5849-8011)
- Carlos Castaño (ORCID: https://orcid.org/0000-0003-1671-7826)
- Rafael Parra‐Medina (ORCID: https://orcid.org/0000-0002-8428-5837)
- Alba Lucía Cómbita (ORCID: https://orcid.org/0000-0001-6295-7316)
- Sandra Quijano (ORCID: https://orcid.org/0000-0003-4452-9291)
- Nathaly Poveda-Garavito
- X. Torres (ORCID: https://orcid.org/0000-0002-2859-6980)
Institutions
- Pontificia Universidad Javeriana (CO)
- Universidad Nacional de Colombia (CO)
- Versiti Blood Center of Wisconsin (US)
- Instituto Nacional de Cancerología (CO)
- Fundación Universitaria de Ciencias de la Salud (CO)
- Hospital Universitario San Ignacio (CO)
- Louisiana State University Health Sciences Center New Orleans (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3389/fimmu.2024.1473909
- Citations
- 6
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- Universidad Nacional de Colombia