DeCGR: an interactive toolkit for deciphering complex genomic rearrangements from Hi-C data
DeCGR is designed specifically for biologists who aim to explore CGRs from Hi-C data. It provides a validation module to ensure the completeness and correctness of CGRs. Additionally, it allows users to generate CGR assembly results and reconstruct the Hi-C map with just one click. DeCGR provides intuitive visualization results for each module, allowing users to easily associate CGRs with Hi-C maps. DeCGR is operable through a user-friendly graphical interface. Source codes are freely available at https://github.com/GaoLabXDU/DeCGR .
Authors
- Lin Gao (ORCID: https://orcid.org/0000-0001-6396-0787)
- Minghui Sun (ORCID: https://orcid.org/0009-0005-0497-4464)
- Yusen Ye (ORCID: https://orcid.org/0000-0001-8687-1058)
- Junping Li (ORCID: https://orcid.org/0000-0001-7377-5518)
Institutions
- Xidian University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1186/s12864-024-11085-5
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China