Phase 2, Multicenter, Open-label, Nonrandomized Study of Neoadjuvant Chemotherapy Liposomal Irinotecan With 5-Fluorouracil, Leucovorin, and Oxaliplatin, Followed by Chemoradiotherapy in Patients With Rectal Cancer in a Watch-and-Wait Program

TNT with 5-fluorouracil, leucovorin, and oxaliplatin and chemoradiation is a safe and effective therapeutic alternative for the management of locally advanced rectal cancer.

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Publication Details

Journal
American Journal of Clinical Oncology
Published
2024-11-29
DOI
https://doi.org/10.1097/coc.0000000000001157
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
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article

Phase 2, Multicenter, Open-label, Nonrandomized Study of Neoadjuvant Chemotherapy Liposomal Irinotecan With 5-Fluorouracil, Leucovorin, and Oxaliplatin, Followed by Chemoradiotherapy in Patients With Rectal Cancer in a Watch-and-Wait Program

Antonio Cubillo, Paloma Peinado, Luka Mihic-Góngora, Carmen Toledano et al.
American Journal of Clinical Oncology
Colorectal Cancer Surgical Treatments
article

Phase 2, Multicenter, Open-label, Nonrandomized Study of Neoadjuvant Chemotherapy Liposomal Irinotecan With 5-Fluorouracil, Leucovorin, and Oxaliplatin, Followed by Chemoradiotherapy in Patients With Rectal Cancer in a Watch-and-Wait Program

Antonio Cubillo, Paloma Peinado, Luka Mihic-Góngora, Carmen Toledano, Ovidio Hernando-Requejo, Rafael Álvarez-Gallego, Valentina Ferri, Lisardo Ugidos, M.Á. Pérez-Escutia, Yolanda Quijano, Cesar Gregorio Muñoz, Eduardo M. Diaz, Carmen Rubio, María Allona, V. Pérez-Dueñas, Ulpiano López, Pilar García‐Alfonso, Mercedes López González, Emilio Vicente, Manuel Martı́nez, Hipólito Durán, Enrique Sanz Garcia, Susana Prados, Justo Gabriel Ortega Anselmi
article en

Abstract

TNT with 5-fluorouracil, leucovorin, and oxaliplatin and chemoradiation is a safe and effective therapeutic alternative for the management of locally advanced rectal cancer.

American Journal of Clinical OncologyVol. 48(3)
University Health Network (CA), Princess Margaret Cancer Centre (CA), Hospital General Universitario Gregorio Marañón (ES), Hospital Universitario 12 De Octubre (ES), HM Hospitales (ES), University Hospital HM Puerta del Sur (ES), Hospital Universitario HM Sanchinarro (ES), Camilo José Cela University (ES)
Good health and well-being
Openalex Percentile: Top 62%
Colorectal Cancer Surgical Treatments
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