Regenerative Hair Transplantation with Autologous Mesenchymal Cells from The Scalp (Regenerative Hair Transplantation)

Introduction: Androgenetic alopecia is a dynamic and chronic disorder of hair thinning and loss that affects men and women before the age of 70. Objective: To describe the technique for preparing follicular progenitor cells (in this case, mesenchymal stem cells) to be used during hair transplantation to optimize the treatment of alopecia since hair follicles are available for clinical stimulation. Materials and Methods: The follicles sectioned during extraction are separated and subjected to fragmentation steps until they reach a pasty solution and are rehydrated. The solution is then diluted, filtered and homogenized. Results/Discussion: Both techniques – hair transplantation and the use of mesenchymal stem cells have scientific evidence widely described in the literature. After extraction, the solution containing autologous mesenchymal stem cells is applied to a selected area of the scalp (hair transplant recipient area) after pre-incisions. Conclusion: Our next studies will describe the phenotyping and mean quantification of hair follicle stem cells by flow cytometry, as well as trichoscopy results and the increase in hair density.