Exploring the effects of erythropoietin treatment on cortical thickness and hippocampal volume in patients with mood disorders undergoing electroconvulsive therapy: A randomized, placebo-controlled trial

EPO treatment may produce a selective increase in the right-side occipito-parietal cortical thickness. In contrast, the thickness of other cognition-relevant structures was not significantly affected. This aligns with our previously reported finding that EPO has a selective effect on autobiographical memory and associated right-side parietal activity in the absence of changes in global cognition. It remains to be investigated whether longer EPO treatment and follow-up assessment may be necessary for overt structural changes in cognition-relevant brain networks.

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Publication Details

Journal
Journal of Psychopharmacology
Published
2024-11-28
DOI
https://doi.org/10.1177/02698811241301224
Primary Topic
Electroconvulsive Therapy Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring the effects of erythropoietin treatment on cortical thickness and hippocampal volume in patients with mood disorders undergoing electroconvulsive therapy: A randomized, placebo-controlled trial

Martin Balslev Jørgensen, Kamilla Woznica Miskowiak, Jeff Zarp Petersen, Kristoffer Brendstrup‐Brix et al.
Journal of Psychopharmacology
Electroconvulsive Therapy Studies
article

Exploring the effects of erythropoietin treatment on cortical thickness and hippocampal volume in patients with mood disorders undergoing electroconvulsive therapy: A randomized, placebo-controlled trial

Martin Balslev Jørgensen, Kamilla Woznica Miskowiak, Jeff Zarp Petersen, Kristoffer Brendstrup‐Brix, Lars Vedel Kessing, Julian Macoveanu, Maj Vinberg
article en

Abstract

EPO treatment may produce a selective increase in the right-side occipito-parietal cortical thickness. In contrast, the thickness of other cognition-relevant structures was not significantly affected. This aligns with our previously reported finding that EPO has a selective effect on autobiographical memory and associated right-side parietal activity in the absence of changes in global cognition. It remains to be investigated whether longer EPO treatment and follow-up assessment may be necessary for overt structural changes in cognition-relevant brain networks.

Journal of PsychopharmacologyVol. 39(2)
University of Copenhagen (DK), Region Zealand (DK), Mental Health Services (DK), Frederiksberg Hospital (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK), Capital Region of Denmark (DK), Sygehus Sønderjylland (DK)
Lundbeckfonden, Augustinus Fonden
Good health and well-being
Openalex Percentile: Top 71%
Electroconvulsive Therapy Studies
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