The Role of the Cytoskeletal Regulatory Protein, Mammalian Enabling Protein (Mena), in Invasion and Metastasis of HPV16-Related Oral Squamous Cell Carcinoma

Mena promotes OSCC invasion and metastasis in HPV-negative OSCC by activating the EMT process. However, Mena expression in OSCC infected with HPV16 is inhibited, thus suppressing its invasion and metastasis ability.

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Publication Details

Journal
Cells
Published
2024-11-28
DOI
https://doi.org/10.3390/cells13231972
Primary Topic
Cancer-related gene regulation
Type
article
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article

The Role of the Cytoskeletal Regulatory Protein, Mammalian Enabling Protein (Mena), in Invasion and Metastasis of HPV16-Related Oral Squamous Cell Carcinoma

Linyang Xie, Junbo Tu, Sijia Na, Hao Cui et al.
Cells
Cancer-related gene regulation
article

The Role of the Cytoskeletal Regulatory Protein, Mammalian Enabling Protein (Mena), in Invasion and Metastasis of HPV16-Related Oral Squamous Cell Carcinoma

Linyang Xie, Junbo Tu, Sijia Na, Hao Cui, Hong Qi, Zhi-Chen Guo, Yuxin Gong, Ming Yu, Xin Yang
article en

Abstract

Mena promotes OSCC invasion and metastasis in HPV-negative OSCC by activating the EMT process. However, Mena expression in OSCC infected with HPV16 is inhibited, thus suppressing its invasion and metastasis ability.

CellsVol. 13(23)
Xi'an Jiaotong University (CN)
No poverty
Openalex Percentile: Top 81%
Cancer-related gene regulation
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