Medicinal potential of adventitious root cultures of <scp><i>Hypericum perforatum</i></scp>: study on antioxidant stress and anti‐melanogenic properties
HpE efficiently protects HepG2 cells from oxidative stress and safeguards the liver in mice by mitigating oxidative damage. Additionally, HpE inhibits melanin synthesis in B16-F10 cells by suppressing tyrosinase activity. These findings suggest that H. perforatum ARs hold potential for use in the development of healthy foods, cosmetics, and pharmaceutical products aimed at antioxidative stress and anti-melanogenesis. © 2024 Society of Chemical Industry.
Authors
- Zhong‐Yu Zhou
- Mei‐Lan Lian (ORCID: https://orcid.org/0000-0002-3420-9908)
- Xuan‐Mei Piao (ORCID: https://orcid.org/0000-0001-6847-7743)
- Xuefeng Li (ORCID: https://orcid.org/0000-0001-8146-8374)
- Zhao Zhang (ORCID: https://orcid.org/0000-0001-5520-9942)
- Han Li (ORCID: https://orcid.org/0000-0003-0846-3846)
- Kexin Zhang (ORCID: https://orcid.org/0000-0002-9224-9465)
- Yuqing Guo (ORCID: https://orcid.org/0009-0008-7320-2793)
Institutions
- Chungbuk National University (KR)
- Yanbian University (CN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1002/jsfa.14058
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China