Transcriptomic Profiling Reveals Differences in Slow‐Twitch and Fast‐Twitch Muscles of a Cigarette Smoke‐Exposed Rat Model
The CS-induced inflammatory responses on soleus muscle are likely mediated via targeting mitochondrial-related signalling, resulting in mitochondrial dysfunction and impaired oxidative capacity. The presumably less active mitochondrial-related signalling in EDL renders it less susceptible to changes towards CS, accounting for differential impacts between muscle types.
Authors
- Shirley P.C. Ngai (ORCID: https://orcid.org/0000-0001-6029-2541)
- Benson Wui-Man Lau (ORCID: https://orcid.org/0000-0002-4552-2780)
- Kwok‐Kuen Cheung (ORCID: https://orcid.org/0000-0001-7367-9171)
- Timothy K. H. Fung (ORCID: https://orcid.org/0000-0001-9719-7687)
- Xia Wang (ORCID: https://orcid.org/0000-0002-3769-1293)
Institutions
- Hong Kong Polytechnic University (HK)
- Chinese University of Hong Kong, Shenzhen (CN)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1002/jcsm.13633
- Citations
- 3
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Hong Kong Polytechnic University