Causal association between epigenetic age acceleration and two pulmonary vascular diseases: pulmonary arterial hypertension and pulmonary embolism—a bidirectional Mendelian study
Our two-sample bidirectional MR analysis suggested that there is no significant association between epigenetic clocks and these two pulmonary vascular diseases.
Authors
- Mengqi Chen (ORCID: https://orcid.org/0000-0001-9728-8511)
- Binqian Ruan (ORCID: https://orcid.org/0000-0001-5340-6483)
- Jieyan Shen (ORCID: https://orcid.org/0009-0004-1117-314X)
- An Wang (ORCID: https://orcid.org/0000-0002-1874-2702)
- Jun Tong
- Chao Wan (ORCID: https://orcid.org/0000-0001-6780-2006)
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- Southern University of Science and Technology (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1186/s13148-024-01778-9
- Citations
- 4
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- National Natural Science Foundation of China