Amino acids in fate decision of porcine immune cells

<p indent="0mm">Amino acids play a key role in the proliferation, development, and immune response of immune cells. This review summarizes the effects of amino acids on intestinal immune function of piglets, and the mechanism of glutamine, γ-aminobutyric acid, arginine and tryptophan in regulating immune cell fate by remodeling cellular metabolism, activation of signal pathways and epigenetic modification. This study provides a theoretical basis for improving the intestinal immune function of piglets through nutritional strategy.

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Publication Details

Journal
Scientia Sinica Vitae
Published
2024-11-29
DOI
https://doi.org/10.1360/ssv-2024-0269
Primary Topic
Genomics, phytochemicals, and oxidative stress
Type
article
Field-Weighted Citation Impact
0.00
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article

Amino acids in fate decision of porcine immune cells

Philip He, Wenkai Ren, Jun Zuo, Jinding Chen et al.
Scientia Sinica Vitae
Genomics, phytochemicals, and oxidative stress
article

Amino acids in fate decision of porcine immune cells

Philip He, Wenkai Ren, Jun Zuo, Jinding Chen, Li Du, Gang Zhao, P L Liu, Hao Wang, Xianfeng Peng, Wenjie Tang, Shijie Liu, Yulong Yin, Bin Peng, J. J. Cui, Hong Tan, DongYan ZHANG
article en

Abstract

<p indent="0mm">Amino acids play a key role in the proliferation, development, and immune response of immune cells. This review summarizes the effects of amino acids on intestinal immune function of piglets, and the mechanism of glutamine, γ-aminobutyric acid, arginine and tryptophan in regulating immune cell fate by remodeling cellular metabolism, activation of signal pathways and epigenetic modification. This study provides a theoretical basis for improving the intestinal immune function of piglets through nutritional strategy.

Scientia Sinica Vitae
Openalex Percentile: Top 81%
Genomics, phytochemicals, and oxidative stress
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