Transcatheter bicuspid venous valve prostheses: fluid mechanical performance testing of artificial nonwoven leaflets
The here introduced design versions act as a platform technology and can be tailored for an intended implantation site. Evaluation of the original and modified valve concept demonstrated efficacy, with limitations at higher loads for original design. At the current state, the modification is preferable for fabrication, as one processing step is eliminated. Moreover, specific design recommendations could be drawn for valves of similar basic structure. Future work will focus on long-term performance and biocompatibility prior to the initiation of preclinical in vivo studies.
Authors
- Andreas Götz (ORCID: https://orcid.org/0000-0003-0463-8741)
- W. J. Schmidt (ORCID: https://orcid.org/0000-0002-0113-3265)
- Heinz Müller
- Niels Grabow
- Julia Schubert
- Sabine Illner (ORCID: https://orcid.org/0000-0002-2033-2964)
- Nicklas Fiedler (ORCID: https://orcid.org/0000-0002-4436-7010)
- Kerstin Lebahn (ORCID: https://orcid.org/0000-0003-1304-1066)
- Jan Oldenburg (ORCID: https://orcid.org/0000-0003-1580-8531)
- Klaus-Peter Schmitz
Institutions
- Institute for ImplantTechnology and Biomaterials (DE)
- University of Rostock (DE)
Publication Details
- Journal
- BioMedical Engineering OnLine
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1186/s12938-024-01316-x
- Citations
- 2
- Primary Topic
- Diagnosis and Treatment of Venous Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.15