Evolution of Self-reported Neuropsychiatric Symptoms After Switching from Dolutegravir/Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide: Results from the Randomized DOBINeuro Trial

Although limited by a low sample size, this study suggests neuropsychiatric tolerability may improve when switching virologically suppressed PLWH from DTG to BIC-based strategies.

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Publication Details

Journal
Infectious Diseases and Therapy
Published
2024-11-29
DOI
https://doi.org/10.1007/s40121-024-01083-1
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
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article

Evolution of Self-reported Neuropsychiatric Symptoms After Switching from Dolutegravir/Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide: Results from the Randomized DOBINeuro Trial

Alessandro Lanari, Silvia Lamonica, Maurizio Zazzi, Antonio Di Biagio et al.
1 links
Infectious Diseases and Therapy
HIV/AIDS drug development and treatment
article

Evolution of Self-reported Neuropsychiatric Symptoms After Switching from Dolutegravir/Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide: Results from the Randomized DOBINeuro Trial

Alessandro Lanari, Silvia Lamonica, Maurizio Zazzi, Antonio Di Biagio, Francesca Bai, Giacomo Zanelli, Lucia Taramasso, L. Trentini, Francesca Alladio, Andrea De Luca, Sabrina Bianchi, Massimiliano Fabbiani, Federica Bonazza, Miriam Durante, Nicoletta Ciccarelli, Nicola Girtler, Ilaria Rancan, Federica Gaia Miraglia, Francesca Lombardi, Barbara Rossetti, Francesca Montagnani, Simona Di Giambenedetto, Federica De Flaviis, Stefano Bonora, Sergio Ferrara, M. Masini, Antonella d’Arminio Monforte
article en

Abstract

Although limited by a low sample size, this study suggests neuropsychiatric tolerability may improve when switching virologically suppressed PLWH from DTG to BIC-based strategies.

Infectious Diseases and TherapyVol. 14(1)
University of Siena (IT), Università degli Studi eCampus (IT), University of Milan (IT), Agostino Gemelli University Polyclinic (IT), Ospedale San Paolo (IT), Ospedale Misericordia - Grosseto (IT), Ospedale Policlinico San Martino (IT), Azienda Usl Toscana Centro (IT), University of Turin (IT), University of Genoa (IT)
Gilead Sciences
Good health and well-being
Openalex Percentile: Top 73%
HIV/AIDS drug development and treatment
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