Genetic Variation in Targets of Antidiabetic Drugs and Amyotrophic Lateral Sclerosis Risk

The complex interaction between hypoglycemic, antioxidation, and anti-inflammatory effects may account for the different results across antidiabetic drug types. These findings provide key evidence to guide the use of antidiabetic drugs and will help to identify novel therapeutic targets in ALS.

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Publication Details

Journal
Biomedicines
Published
2024-11-29
DOI
https://doi.org/10.3390/biomedicines12122733
Citations
3
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
1.11

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article

Genetic Variation in Targets of Antidiabetic Drugs and Amyotrophic Lateral Sclerosis Risk

Dongsheng Fan, Mengxia Wan, Junyan Huo, Tao Huang et al.
3 citations
Biomedicines
Amyotrophic Lateral Sclerosis Research
1.11
article

Genetic Variation in Targets of Antidiabetic Drugs and Amyotrophic Lateral Sclerosis Risk

Dongsheng Fan, Mengxia Wan, Junyan Huo, Tao Huang, Linjing Zhang, Yu Fu
article en
3 citations

Abstract

The complex interaction between hypoglycemic, antioxidation, and anti-inflammatory effects may account for the different results across antidiabetic drug types. These findings provide key evidence to guide the use of antidiabetic drugs and will help to identify novel therapeutic targets in ALS.

BiomedicinesVol. 12(12)
Capital Medical University (CN), Peking University (CN), National Health and Family Planning Commission (CN), Peking University Third Hospital (CN), Beijing Friendship Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 20%
Amyotrophic Lateral Sclerosis Research
1.11
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