Research progress on mechanism of EBV infection

<p indent="0mm">Epstein-barr virus (EBV) belongs to the human herpesvirus gamma subfamily and infects more than 90% of the world’s population. EBV infection causes millions of new cases of noncancer and more than 200000 new cases of cancer each year. Human B cells and epithelial cells are the main host cells of EBV. The invasion mechanism of EBV into host cells is very complex, which requires multiple viral envelope glycoproteins to cooperate with different host factors to determine its host tropism. In recent years, scientists have deepened their research on the mechanism of EBV infection, which provides new ideas for the precise prevention and treatment of EBV-related diseases. This review will systematically introduce the current status and prospects of the research on the mechanism of EBV infection.

Authors

Publication Details

Journal
Scientia Sinica Vitae
Published
2024-11-29
DOI
https://doi.org/10.1360/ssv-2024-0186
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Research progress on mechanism of EBV infection

Hua Zhang
Scientia Sinica Vitae
Viral-associated cancers and disorders
article

Research progress on mechanism of EBV infection

Hua Zhang
article en

Abstract

<p indent="0mm">Epstein-barr virus (EBV) belongs to the human herpesvirus gamma subfamily and infects more than 90% of the world’s population. EBV infection causes millions of new cases of noncancer and more than 200000 new cases of cancer each year. Human B cells and epithelial cells are the main host cells of EBV. The invasion mechanism of EBV into host cells is very complex, which requires multiple viral envelope glycoproteins to cooperate with different host factors to determine its host tropism. In recent years, scientists have deepened their research on the mechanism of EBV infection, which provides new ideas for the precise prevention and treatment of EBV-related diseases. This review will systematically introduce the current status and prospects of the research on the mechanism of EBV infection.

Scientia Sinica Vitae
Openalex Percentile: Top 62%
Viral-associated cancers and disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.