The incidence of pancreatic cancer in women with a <i>BRCA1</i> or <i>BRCA2</i> mutation
The lifetime risk of pancreatic cancer is approximately 2% in women with a BRCA1 mutation and 3% for women with a BRCA2 mutation. The poor survival in hereditary pancreatic cancer underscores the need for novel antitumoral strategies.
Authors
- Christian Fridolin Singer (ORCID: https://orcid.org/0000-0003-1294-0027)
- Jan Lubiński (ORCID: https://orcid.org/0000-0003-2931-3003)
- Tomasz Huzarski (ORCID: https://orcid.org/0000-0003-3857-4854)
- William D. Foulkes (ORCID: https://orcid.org/0000-0001-7427-4651)
- Louise Bordeleau (ORCID: https://orcid.org/0000-0003-2111-0228)
- Bryson W. Katona (ORCID: https://orcid.org/0000-0001-8186-9119)
- Tuya Pal (ORCID: https://orcid.org/0000-0001-8009-2475)
- Charis Eng (ORCID: https://orcid.org/0000-0002-3693-5145)
- Susan Randall Armel (ORCID: https://orcid.org/0000-0001-5016-3148)
- Amber M. Aeilts (ORCID: https://orcid.org/0000-0001-8907-7853)
- Dana Zakalik (ORCID: https://orcid.org/0000-0002-6212-7942)
- Olufunmilayo I. Olopade (ORCID: https://orcid.org/0000-0002-9936-1599)
- Susan L. Neuhausen (ORCID: https://orcid.org/0000-0001-5053-0390)
- Robert Fruscio (ORCID: https://orcid.org/0000-0001-5688-2194)
- Andrea Eisen (ORCID: https://orcid.org/0000-0001-8037-9556)
- Beth Y. Karlan (ORCID: https://orcid.org/0000-0002-9451-2933)
- Joanne Kotsopoulos (ORCID: https://orcid.org/0000-0001-9624-4218)
- Steven A. Narod (ORCID: https://orcid.org/0000-0001-5798-0626)
- Pål Møller (ORCID: https://orcid.org/0000-0001-8211-8237)
- Ping Sun
- Nadine Tung
- Rebecca Raj
Institutions
- Oslo University Hospital (NO)
- Beth Israel Deaconess Medical Center (US)
- Cleveland Clinic (US)
- Sunnybrook Health Science Centre (CA)
- University of California, Los Angeles (US)
- University of Toronto (CA)
- Juravinski Cancer Centre (CA)
- Princess Margaret Cancer Centre (CA)
- The Ohio State University Wexner Medical Center (US)
- University of Chicago (US)
- Comprehensive Cancer Center Vienna (AT)
- City of Hope (US)
- Public Health Ontario (CA)
- Beaumont Hospital, Royal Oak (US)
- Cancer Genetics (United States) (US)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- International Hereditary Cancer Center (PL)
- McGill University (CA)
- The Ohio State University (US)
- University of Milano-Bicocca (IT)
- Medical University of Vienna (AT)
- University of Pennsylvania (US)
- Pomeranian Medical University (PL)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Cancer
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1002/cncr.35666
- Citations
- 13
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 3.67
Funders
- Peter Gilgan Foundation
- Canadian Institutes of Health Research