Immunological characteristics in elderly COVID-19 patients: a post-COVID era analysis

Lymphocytopenia and the cytokine storm onset are significant predictors of an unfavorable prognosis in elderly patients. The decrease in CD4<sup>+</sup> T cells among elderly patients is detrimental to disease recovery, and the biological pathways regulated by these cells could potentially heighten vulnerability to SARS-CoV-2 infection, thereby exacerbating the development of associated complications.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2024-11-29
DOI
https://doi.org/10.3389/fcimb.2024.1450196
Citations
1
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
0.39
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article

Immunological characteristics in elderly COVID-19 patients: a post-COVID era analysis

Yunhui Li, Yajie Wang, Jing Liang, Yuan Chen
1 citations
Frontiers in Cellular and Infection Microbiology
COVID-19 Clinical Research Studies
0.39
article

Immunological characteristics in elderly COVID-19 patients: a post-COVID era analysis

Yunhui Li, Yajie Wang, Jing Liang, Yuan Chen
article en
1 citations

Abstract

Lymphocytopenia and the cytokine storm onset are significant predictors of an unfavorable prognosis in elderly patients. The decrease in CD4<sup>+</sup> T cells among elderly patients is detrimental to disease recovery, and the biological pathways regulated by these cells could potentially heighten vulnerability to SARS-CoV-2 infection, thereby exacerbating the development of associated complications.

Frontiers in Cellular and Infection MicrobiologyVol. 14
Capital Medical University (CN), Beijing Ditan Hospital (CN)
Good health and well-being
Openalex Percentile: Top 34%
COVID-19 Clinical Research Studies
0.39
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