Longitudinal Quantitative <scp>MRI</scp> Provides Responsive Outcome Measures for Early and Late Muscle Changes in <scp>ALS</scp>

High responsiveness and low variability make quantitative muscle MRI a novel and complementary outcome measure for ALS clinical trials.

Authors

Catherine Bresee (ORCID: https://orcid.org/0000-0002-5710-4906)
Pablo Avalos (ORCID: https://orcid.org/0000-0002-5313-5334)
John S. Thornton (ORCID: https://orcid.org/0000-0003-3248-8437)
Frank Diaz (ORCID: https://orcid.org/0000-0003-3526-1852)
Jasper M. Morrow (ORCID: https://orcid.org/0000-0001-6879-8539)
Stephen Wastling (ORCID: https://orcid.org/0000-0003-4648-9932)
Clive N. Svendsen (ORCID: https://orcid.org/0000-0001-8696-3446)
Pamela J. Shaw (ORCID: https://orcid.org/0000-0002-8925-2567)
Richard A. Lewis (ORCID: https://orcid.org/0000-0002-1140-4575)
Peggy Allred
Nick Zafeiropoulos
Abeer Asaab

Institutions

Cedars-Sinai Medical Center (US)
Novartis (United States) (US)
National Hospital for Neurology and Neurosurgery (GB)
University College London (GB)

Publication Details

Journal: Muscle & Nerve
Published: 2024-11-29
DOI: https://doi.org/10.1002/mus.28306
Citations: 3
Primary Topic: Amyotrophic Lateral Sclerosis Research
Type: article
Field-Weighted Citation Impact: 1.11

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article

Longitudinal Quantitative MRI Provides Responsive Outcome Measures for Early and Late Muscle Changes in ALS

Catherine Bresee, Pablo Avalos, John S. Thornton, Frank Diaz et al.

Nov 29, 2024

3 citations

Muscle & Nerve

Amyotrophic Lateral Sclerosis Research

1.11

article

Longitudinal Quantitative MRI Provides Responsive Outcome Measures for Early and Late Muscle Changes in ALS

Catherine Bresee, Pablo Avalos, John S. Thornton, Frank Diaz, Jasper M. Morrow, Stephen Wastling, Clive N. Svendsen, Pamela J. Shaw, Richard A. Lewis, Peggy Allred, Nick Zafeiropoulos, Abeer Asaab

November 29, 2024article en

3 citations

Abstract

High responsiveness and low variability make quantitative muscle MRI a novel and complementary outcome measure for ALS clinical trials.

Muscle & NerveVol. 71(2)

Cedars-Sinai Medical Center (US), Novartis (United States) (US), National Hospital for Neurology and Neurosurgery (GB), University College London (GB)

Openalex Percentile: Top 20%

Amyotrophic Lateral Sclerosis Research

1.11

DOI Source OpenAlex

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Longitudinal Quantitative <scp>MRI</scp> Provides Responsive Outcome Measures for Early and Late Muscle Changes in <scp>ALS</scp> — Catherine Bresee, Pablo Avalos, et al. · Muscle & Nerve (2024) | TGRS Research Map | TGRS