SURVEY OF THE INCREASING RATE OF BLOOD URIC ACID IN PEOPLE UNDER 40 AGES

Introduction: Hyperuricemia is known as a risk factor for gout and cardiovascular disease [1,2,3]. Economic development along with changes in lifestyle, diet of people ≤ 40 years old are the risks of hyperuricemia. We conducted this study to investigate the hyperuricemia rate, the correlation between hyperuricemia and certain foods and pre-existing conditions. Methods: A cross-sectional study describing 285 subjects with general health check-ups at the University Medical Center 2 from May to July 2022. The results were collected and divided into groups related to age, gender, BMI, pre-existing conditions, lifestyle, and diet for correlation analysis. Results: The overall rate of hyperuricemia was 41.40%, the rate in men was higher than women (p < 0.001). Hyperuricemia and BMI, pre-existing condition, smoking, drinking alcohol, drinking milk with were correlated. The rate of increasing blood uric acid levels and this correlation were respectively: obesity 49.39% (BMI ≥ 23), OR=2.22, 95% CI: 1.32-3.75; pre-existing conditions 75%, OR=8.5, 95% CI: 1.79-79.68; smoking 50.57%, OR=1.71, 95% CI: 1.00-2.95 and drinking alcohol 52.94%, OR=1.72, 95% CI: 1.31-2.25. The rate of hyperuricemia in the group who drank milk (31.78%) was lower than the group who did not (47.19%), p = 0.011, and reduced the risk of hyperuricemia by 48% compared to the people who did not (OR = 0.52, 95% CI: 0.30-0.89). Conclusions: The rate of hyperuricemia in people ≤ 40 years old was 41.40%. The factors affecting blood uric acid levels were BMI, pre-existing conditions, smoking, and drinking alcohol increased the risk; drinking milk reduced the risk.