Commissioning a clinical proton pencil beam scanning beamline for pre-clinical ultra-high dose rate irradiations on a cyclotron-based system
We successfully modified a clinical system to perform UHDR pre-clinical experiments. As part of our pre-clinical experiments, we observed the FLASH effect concerning mice survival.
Authors
- Juergen Meyer (ORCID: https://orcid.org/0000-0003-4350-2222)
- Marco Schwarz (ORCID: https://orcid.org/0000-0001-6964-7732)
- Danielle P. Johnson Erickson
- Ning Cao (ORCID: https://orcid.org/0000-0002-3929-8604)
- Jatinder Saini
- Séverine Rossomme (ORCID: https://orcid.org/0000-0001-8560-7642)
- Ramesh Rengan (ORCID: https://orcid.org/0000-0001-5379-536X)
- François Vander Stappen
- Sunan Cui (ORCID: https://orcid.org/0000-0002-8846-9449)
- C. Bloch (ORCID: https://orcid.org/0000-0002-8035-0056)
- Jing Zeng (ORCID: https://orcid.org/0000-0001-7388-8926)
- Clemens Grassberger (ORCID: https://orcid.org/0000-0002-4425-4489)
- Tony Wong (ORCID: https://orcid.org/0000-0002-7759-0585)
- Eric C. Ford
- Matt Ruth
- Valerie Gorman
Institutions
- University of Washington (US)
- Fred Hutch Cancer Center (US)
- Ion Beam Applications (Belgium) (BE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3389/fonc.2024.1460288
- Citations
- 5
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Fred Hutchinson Cancer Research Center