Copper‐Catalyzed Regioselective Reaction for Arylselenation of Unprotected Pyrazoles Using Selenium Powder
Abstract A new and convenient Cu‐catalyzed three‐component reaction of N‐unsubstituted pyrazoles with Se powder and aryl iodides has been established. The protocol presents a broad substrate scope, good functional group tolerance, and high regioselectivity. The utility of this procedure is further established by gram‐scale synthesis as well as the diversified transformations of 4‐organylselanyl‐1 H ‐pyrazoles to useful compounds.
Authors
- Yi Wu (ORCID: https://orcid.org/0000-0003-1386-1304)
- Suo Gao
- Xin Zha (ORCID: https://orcid.org/0009-0000-7871-8125)
- Jianta Wang (ORCID: https://orcid.org/0000-0002-2007-0925)
- Cong Wang (ORCID: https://orcid.org/0000-0003-2456-4647)
- Lei Tang (ORCID: https://orcid.org/0000-0003-1273-9040)
- Xia Mu (ORCID: https://orcid.org/0000-0001-9401-9287)
- Yusheng Pu
- Jinghua Ruan
- Bing Wang (ORCID: https://orcid.org/0000-0002-3822-5905)
Institutions
- Guiyang Medical University (CN)
- Guizhou University (CN)
- Sichuan University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- ChemistrySelect
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1002/slct.202403594
- Citations
- 3
- Primary Topic
- Organoselenium and organotellurium chemistry
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Guizhou University
- Natural Science Foundation of Guizhou Province