Identification and validation of respiratory subphenotypes in patients with COVID-19 acute respiratory distress syndrome undergoing prone position
Our study successfully identified and validated two distinct subphenotypes of COVID-19 ARDS based on key respiratory parameters. The findings suggest potential implications for better patient stratification, risk assessment, and treatment personalization. Future research is warranted to explore the utility of these novel subphenotypes for guiding targeted therapeutic strategies in COVID-19 ARDS.
Authors
- Mônica Rodrigues da Cruz (ORCID: https://orcid.org/0000-0003-0641-0097)
- Fernanda Lima‐Setta (ORCID: https://orcid.org/0000-0001-9171-2043)
- Pedro Azambuja (ORCID: https://orcid.org/0000-0002-2834-0061)
- André Miguel Japiassú (ORCID: https://orcid.org/0000-0002-9444-9890)
- Denise Machado Medeiros (ORCID: https://orcid.org/0000-0001-7921-5941)
- K. Torres (ORCID: https://orcid.org/0009-0006-1496-5059)
Institutions
- Universidade do Estado do Rio de Janeiro (BR)
- Hospital Universitário Pedro Ernesto (BR)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1186/s13613-024-01414-y
- Citations
- 7
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.93
Funders
- Fundação Oswaldo Cruz