On the origin of mitosis-derived human embryo aneuploidy
Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell imaging, three recent studies identify spindle architecture and positioning features that could provide insights into why early embryos are predisposed to chromosomal abnormalities.
Authors
- Binyam Mogessie (ORCID: https://orcid.org/0000-0002-0702-6356)
- Madison Gowett
- Jiyeon Leem (ORCID: https://orcid.org/0000-0001-5262-9730)
- Sarah Bolarinwa (ORCID: https://orcid.org/0009-0002-8098-8698)
Institutions
- Yale University (US)
Publication Details
- Journal
- Nature Communications
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1038/s41467-024-54953-0
- Citations
- 4
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 4.44
Funders
- Wellcome
- Wellcome Trust
- National Research Foundation
- National Research Foundation of Korea
- National Institutes of Health
- National Institute of General Medical Sciences