Targeting Radiation Resistance in Oesophageal Adenocarcinoma with Pyrazinib-Functionalised Gold Nanoparticles
These results collectively confirm that P3, in its conjugated formulation with gold nanoparticles, retains its therapeutic properties, highlighting the potential of AuNP-P3 as a novel therapeutic radiosensitizer for oesophageal adenocarcinoma and supporting its further development for clinical applications.
Authors
- Narayanasamy Ravi (ORCID: https://orcid.org/0000-0001-9794-622X)
- Niamh Lynam‐Lennon (ORCID: https://orcid.org/0000-0001-8659-4943)
- Breandán N. Kennedy (ORCID: https://orcid.org/0000-0001-7991-4689)
- Jacintha O’Sullivan
- Gabriele Vella (ORCID: https://orcid.org/0000-0002-5418-5552)
- Adriele Prina‐Mello (ORCID: https://orcid.org/0000-0002-4371-2214)
- Fiona O’Connell (ORCID: https://orcid.org/0000-0002-3641-4374)
- John V. Reynolds (ORCID: https://orcid.org/0000-0002-5501-9521)
- Jolanda Spadavecchia
- Meghana Menon
- Simone Marcone (ORCID: https://orcid.org/0000-0001-5516-4000)
- Memona Khan
- Claire Donohoe (ORCID: https://orcid.org/0000-0003-2468-9431)
- Stephen G. Maher (ORCID: https://orcid.org/0000-0003-0126-7906)
- Marzia Pendino
Institutions
- University College Dublin (IE)
- Centre National de la Recherche Scientifique (FR)
- Université Paris Cité (FR)
- Trinity College Dublin (IE)
- Université Sorbonne Paris Nord (FR)
- Sorbonne Paris Cité (FR)
- Chimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques
Publication Details
- Journal
- Cancers
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3390/cancers16234007
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Research Board